Monday, 16 June 2014

GATK: download dbsnp_138.b37.vcf.gz

The login information is provided by http://www.broadinstitute.org/gatk/guide/article?id=1215.

"ftp ftp.broadinstitute.org", and at prompt enter the username "gsapubftp-anonymous".

At the "/bundle/2.8/b37" directory, use "get dbsnp_138.b37.vcf.gz" to download the latest database of known polymorphic sites to the current local working directory.

This file is used in BaseRecalibrator to supply the parameter "-knownSites" (full details available from http://www.broadinstitute.org/gatk/gatkdocs/org_broadinstitute_sting_gatk_walkers_bqsr_BaseRecalibrator.html).


No comments:

Post a Comment