Histone Variant H3.3

Cited from the Paper Distinct factors control histone variant H3.3 localization at specific genomic regions

Mammalian cells express three major types of non-centromeric histone H3 variants, H3.1, H3.2, and H3.3. Although histone H3.3 differs from H3.2 and H3.1 at only 4 or 5 amino acids, H3.3 is specifically enriched at transcriptionally active genes and regulatory elements in non-pluripotent cells.

Practical Machine Learning: Methods and Algorithmics

Practical machine learning: methods and algorithmics

Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data

Inference of RNA Polymerase II Transcription Dynamics from Chromatin Immunoprecipitation Time Course Data

Improving small RNA-seq by using a synthetic spike-in set for size-range quality control together with a set for data normalization

Improving small RNA-seq by using a synthetic spike-in set for size-range quality control together with a set for data normalization

Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution

Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution

Pre-Closing Walkthrough

The Pre-Closing Walkthrough

Method for Producing Genome Signal Track

Cited from the paper "Cooperative Binding of Transcription Factors Orchestrates Reprogramming"

Genome signal tracks of features (TFs, histone marks, ATAC-seq and RNA-seq) were calculated by partitioning the genome into non-overlapping bins of fixed size (100b for TFs, ATAC-seq and RNA-seq, and 25bp for the histone marks). RPKM values were calculated for each bin using the number of sequencing reads that overlap with the corresponding bin. For histone marks, each read was extended by 200 bp in the direction of the alignment.