What does the plot of mutational signature analysis mean?
Interpreting the signature results
Why are there only 96 triplets?
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This classification has 96 possible mutations since there are six classes of base substitution C>A, C>G, C>T, T>A, T>C, T>G (all substitutions are referred to by the pyrimidine of the mutated Watson-Crick base pair) and the bases immediately 5’ and 3’ to each mutated base are incorporated.
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